Thesis Project Form
Title (tentative): Determinants of Renal Tissue Oxygenation as Measured with BOLD-MRI in Chronic Kidney Disease| Thesis advisor(s): Fato Marco Massimo, Benedetta Toselli (DIBRIS), Beatrice Damasio (GasliniI | E-mail: |
| Address: Via All'Opera Pia, 13 - 16145 Genova | Phone: (+39) 010 33 52789 |
Description
Motivation and application domain
Experimentally renal tissue hypoxia appears to play an important role in the pathogenesis of chronic kidney disease (CKD)
General objectives and main activities
In this study we measured renal tissue oxygenation and its determinants in humans using blood oxygenation level-dependent magnetic resonance imaging (BOLD-MRI) under standardized hydration conditions.
Different coronal slices were selected, and a multi gradient echo sequence was used to acquire T2* weighted images.
Different coronal slices were selected, and a multi gradient echo sequence was used to acquire T2* weighted images.
Training Objectives (technical/analytical tools, experimental methodologies)
Obiettivi
- study different tools and methods of applying BOLD-MRI analysis on CKD
- select best tool for BOLD-MRI analysis and test feasibility on images of children and neonates
- study different tools and methods of applying BOLD-MRI analysis on CKD
- select best tool for BOLD-MRI analysis and test feasibility on images of children and neonates
Place(s) where the thesis work will be carried out: DIBRIS - Gaslini
Additional information
Maximum number of students: 1