Thesis Project Form
Title (tentative): Stimulation of neuronal networks derived from human induced pluripotent stem cells coupled to MEAs: characterization of the electrophysiological response of stimuli evoked| Thesis advisor(s): Martinoia Sergio | E-mail: |
| Address: | Phone: (+39) 010 33 52980 |
Description
Motivation and application domain
Neuronegineering and Neurotechnologies. Micro-Electrode-Arrays and induced pluripotent stem cells
General objectives and main activities
- Realization of experimental protocols for the electrical stimulation of neural networks derived from human induced pluripotent cells coupled to micro-electrode matrices.
- Realization of experimental protocols for the chemical stimulation of neural networks derived from human induced pluripotent cells coupled to micro-electrode matrices.
- Implementation of software tools for data analysis, in particular for the study of network dynamics.
- Realization of experimental protocols for the chemical stimulation of neural networks derived from human induced pluripotent cells coupled to micro-electrode matrices.
- Implementation of software tools for data analysis, in particular for the study of network dynamics.
Training Objectives (technical/analytical tools, experimental methodologies)
Instruments acquired at the end of the thesis:
- Use of data acquisition platforms (MCS)
- Cell culture methods
- Software tools for data analysis
- Use of data acquisition platforms (MCS)
- Cell culture methods
- Software tools for data analysis
Place(s) where the thesis work will be carried out: Neuroengineering and Neurotechonolgies Lab (N2Lab)
Additional information
Maximum number of students: 1