Thesis Project Form
Title (tentative): Recordings and characterization of the electrophysiological activity of cortical ALS neurons coupled to MEAs| Thesis advisor(s): Massobrio Paolo, Martina Brofiga | E-mail: |
| Address: Via All'Opera Pia, 13 - 16145 Genova | Phone: (+39) 010 33 52761 |
Description
Motivation and application domain
Understanding in a simplified in vitro models possible modifications induced by ALS
General objectives and main activities
Development of a new experimental protocol to cultivate complex central and peripheral neuronal networks affected by ALS to MEAs. Characterization of their electrophysiological activity
Training Objectives (technical/analytical tools, experimental methodologies)
Cell culture procedures; Microscopy techniques; MEA-based set-up; Data analysis (MATLAB-based) algorithms.
Place(s) where the thesis work will be carried out: DIBRIS
Additional information
Pre-requisite abilities/skills: Computational Neuroscience, Matlab Programming, Lab
Curriculum: Neuroengineering
Maximum number of students: 1