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Thesis Project Form

Title (tentative): Metal ions doping to enhance the bioactivity of calcium phosphates as fillers in 3D printing of dental devices

Thesis advisor(s): Lagazzo Alberto E-mail:
Address: via Opera Pia 15, 2° piano Phone: (+39) 010353 - 6037
Description

Motivation and application domain
Calcium phosphates are used as bone substitutes due to their biocompatibility and osteoconductive properties.
The doping with metal ions of calcium phosphates can be a method to improve their bioactivity and other parameters, such as their antibacterial, anti-inflammatory, antiosteoporotic, or angiogenic properties. Three types of metal ions can be considered: Zn, Sr, and Cu. The resulting material will be used as a filler in polymer matrices for 3D printing of dental devices.

General objectives and main activities
The experimental thesis will be conducted in the Materials Engineering Laboratory, where calcium phosphates doped with metallic elements will be prepared through precipitation processes or solid-state reactions between salts. The resulting material will be characterized from a chemical-physical, microstructural, and mechanical perspective to evaluate the changes that these doping elements can induce on the phosphate's properties.

Training Objectives (technical/analytical tools, experimental methodologies)
The student will prepare calcium phosphates doped; he/she will use instrumentation for microstructural (SEM), chemical-physical (X-ray diffractometry, FT-IR, IR-ATR, wettability), thermal (TG-DTA, dilatometry), and mechanical analysis of ceramic materials.

Place(s) where the thesis work will be carried out: Laboratorio Ingegneria dei Materiali del DICCA

Additional information

Pre-requisite abilities/skills: Chemistry and Materials Science

Maximum number of students: 2